Status:
ACTIVE_NOT_RECRUITING
Effect of Non-nutritive Sweeteners of High Sugar Sweetened Beverages on Metabolic Health and Gut Microbiome
Lead Sponsor:
Laval University
Conditions:
Gut Microbiota
Metabolic Syndrome
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Increasing evidence suggest that artificial sweeteners such as saccharin, aspartame and sucralose may not be as metabolically safe as they first appeared, and it has been proposed that their consumpti...
Eligibility Criteria
Inclusion
- Men and women in good health
- Soft drinks consumers (between 4 cans/week to 4 cans/day)
Exclusion
- Metabolic disorders (hypertension, diabetes, hypercholesterolemia)
- Daily consumption of more than 4 cans of soft drinks
- Regular use of medication affecting study parameters
- Change of medication (type or dose) in the last year
- Use of antibiotics in the last 3 months
- Change in natural health product use in the last 3 months
- More than 2 alcohol drinks par day
- Weight change of more than 5% in the last 3 months
- Surgery in the last 3 months or planed during the study
- Allergy or intolerance for products contained in soft drinks
Key Trial Info
Start Date :
October 18 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2025
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT03259685
Start Date
October 18 2017
End Date
December 1 2025
Last Update
December 26 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Laval University
Québec, Canada, G1V0A6