Status:

COMPLETED

Comparison of Cardiotoxicity Induced by Selective Estrogen REceptor Modulators and aNti-Aromatase

Lead Sponsor:

Groupe Hospitalier Pitie-Salpetriere

Conditions:

Cardiac Affections

Eligibility:

All Genders

18-100 years

Brief Summary

Selective estrogen receptor modulators and aromatase inhibitors for the treatment of breast cancer seems to have an impact on the cardio-vascular system. This study investigates reports of cardiovascu...

Detailed Description

Hormone replacement therapies and contraceptive pills are responsible of a wide range of cardio-vascular side effects, particularly thrombo-embolic disorders and ischemic heart disease. The difference...

Eligibility Criteria

Inclusion

  • Case reported in the Eudravigilance from 01/2002 to 08/2017
  • Adverse event reported were including the MedDRA terms: SOC Cardiac Affections and the HLT Death and Sudden Death

Exclusion

  • \-

Key Trial Info

Start Date :

January 1 2001

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 14 2017

Estimated Enrollment :

20000 Patients enrolled

Trial Details

Trial ID

NCT03259711

Start Date

January 1 2001

End Date

August 14 2017

Last Update

October 18 2018

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Centre Régional de Pharmaco-vigilance - Paris, Pitié-Salpétrière

Paris, Île-de-France Region, France