Status:

COMPLETED

Enhancement of PTSD Treatment With Computerized Executive Function Training

Lead Sponsor:

VA Office of Research and Development

Conditions:

Posttraumatic Stress Disorder

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

This study focuses on helping Iraq and Afghanistan Veterans with posttraumatic stress disorder (PTSD) benefit fully from therapy by first enhancing their thinking abilities. PTSD has been associated w...

Detailed Description

PTSD affects approximately 14% of OEF/OIF Veterans and leads to considerable personal and societal costs (e.g., increased morbidity, reduced work productivity, poorer relationships). Although cognitiv...

Eligibility Criteria

Inclusion

  • Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans enrolled at Veterans Affairs San Diego Healthcare System (VASDHS)
  • aged 18-55
  • current posttraumatic stress disorder (PTSD) diagnosis
  • endorsement of cognitive complaints
  • no pending medication changes
  • English-speaking.

Exclusion

  • active substance use disorder in the last month
  • suicidal intent or attempt within the last month
  • schizophrenia, psychotic disorder and/or bipolar disorder
  • dementia
  • premorbid IQ \< 70
  • participation in other concurrent PTSD intervention studies
  • previous completion of more than 4 Cognitive Processing Therapy (CPT) sessions
  • history of a documented neurological disorder (e.g., Parkinson's disease, multiple sclerosis, epilepsy)
  • moderate to severe traumatic brain injury (TBI) (i.e., loss of consciousness greater than 30 minutes or post-traumatic amnesia greater than 24 hours).

Key Trial Info

Start Date :

July 2 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2022

Estimated Enrollment :

82 Patients enrolled

Trial Details

Trial ID

NCT03260127

Start Date

July 2 2018

End Date

October 31 2022

Last Update

April 1 2024

Active Locations (1)

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1

VA San Diego Healthcare System, San Diego, CA

San Diego, California, United States, 92161