Status:

RECRUITING

Circulating Tumor DNA to Monitor Response to Neoadjuvant Chemotherapy in Breast Cancer

Lead Sponsor:

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Conditions:

Breast Cancer

Eligibility:

FEMALE

18-70 years

Brief Summary

Investigators aim to investigate whether circulating tumor DNA is a sensitive marker to evaluate patients' response to neoadjuvant chemotherapy

Detailed Description

Neoadjuvant chemotherapy(NAC) is traditionally for locally advanced disease, converting an inoperable to a resectable tumor.In recent years, it has become an option for patients of lower tumor stage t...

Eligibility Criteria

Inclusion

  • Female patients undergoing NAC
  • Age: 18-70 yrs
  • Any menopausal status
  • Any hormal receptor status

Exclusion

  • Metastasis discovered during NAC
  • Lost more than 2 blood samples during NAC and surgery

Key Trial Info

Start Date :

September 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT03260192

Start Date

September 1 2013

End Date

December 1 2025

Last Update

January 10 2024

Active Locations (1)

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1

Sunyat-sen Memorial Hospital

Guandong, Guangdong, China