Status:

COMPLETED

Ranibizumab Plus Indomethacin

Lead Sponsor:

Università degli Studi di Brescia

Conditions:

Macular Edema

Eligibility:

All Genders

40+ years

Phase:

PHASE4

Brief Summary

To evaluate whether indomethacin eyedrops plus intravitreal ranibizumab (IVR) provides additional benefit over IVR monotherapy for treatment of choroidal neovascularization (CNV) in age-related macula...

Eligibility Criteria

Inclusion

  • provision of written informed consent and compliance with study assessments for the full duration of the study
  • age \> 40 years
  • presence of treatment-naïve neovascular AMD.

Exclusion

  • any previous intravitreal treatment
  • previous laser treatment in the study eye
  • myopia \> 7 diopters in the study eye
  • concurrent eye disease in the study eye that could compromise visual acuity (e.g., diabetic retinopathy and advanced glaucoma)
  • concurrent corneal epithelial disruption or any condition that would affect the ability of the cornea to heal
  • known sensitivity to any component of the formulations being investigated.

Key Trial Info

Start Date :

January 7 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 25 2017

Estimated Enrollment :

58 Patients enrolled

Trial Details

Trial ID

NCT03261635

Start Date

January 7 2016

End Date

July 25 2017

Last Update

August 25 2017

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