Status:

COMPLETED

Evaluation of Biocompatibility and Performances of 4 Dialyzers in Different Mode Treatments

Lead Sponsor:

Hemotech

Conditions:

End Stage Renal Disease

Inflammation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Prospective multicenter randomized cross-over study Number of patients : 32 (8 patients per group) Obtain objectives data to advise each hemodialyzer according to dialysis treatment and patient profil...

Detailed Description

Medical devices studied : * Leoceed 21HX, hemodialyzer, High permeability PS membrane 2,1 m² , made by Nx Stage in Germany * Polypure 22S, hemodialyzer, High permeability PS membrane 2,2 m² , made by...

Eligibility Criteria

Inclusion

  • Adult patient with chronic kidney disease dialyzed for at least one month and treated with the treatment mode that we will test
  • Patient using post-dilution HDF mode have to use EuDIAL volume guidelines (20-22L minimum)
  • Patient treated before with high permeability membrane
  • Patient with vascular access allowing a blood flow rate with a minimum of 300 mL/min
  • Patient treated with a high surface area dialyzer ≥ 1,8 m²
  • Patient covered by the social French health organism
  • Patient informed of the study goals and having signed the informed consent

Exclusion

  • Patient with a vascular access not allowing a blood flow rate minimum of 300 mL/min
  • Patient with a fast progressive chronic disease
  • Patient with an uncontrolled anemia
  • Patient refusing to sign the informed consent
  • Pregnant or nursing patient
  • Pediatric patient
  • Patient under tutorship

Key Trial Info

Start Date :

November 21 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2018

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT03262272

Start Date

November 21 2016

End Date

October 31 2018

Last Update

February 21 2019

Active Locations (1)

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AIDER-Lapeyronie

Montpellier, France, 34295