Status:
COMPLETED
The Stroke Volume Optimization of Goal Directed Fluid Therapy During Radical Cystectomy
Lead Sponsor:
Mansoura University
Conditions:
Radical Cystectomy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Although fluid therapy is of paramount value in anesthetic practice, there is no guideline available for perioperative fluid management in major abdominal surgery. So, there is a need to establish whe...
Detailed Description
Study protocol: Patients will be randomly assigned to one of two equal groups, according to computer-generated randomization sequence into: * Stroke volume optimization group (SVO group). * Central ...
Eligibility Criteria
Inclusion
- Adult patients with American Society of Anesthesiologists (ASA) physical status I - II scheduled for radical cystectomy and urinary diversion for muscle invasive urinary bladder carcinoma .
- Both sexes
Exclusion
- Patients younger than 18 years
- Body mass index (BMI) \< 25 and \>35.
- Patients with any contraindications to epidural anesthesia (patient refusal, local skin infection, previous spine surgery and coagulopathy).
- Those with known allergy to local anesthetics.
- Patients with major cardiovascular problems with ejection fraction \< 40 .
- Renal impairment with serum creatinine \>1.8 mg/dl
- Patients with hepatic dysfunction will be excluded.
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 10 2020
Estimated Enrollment :
172 Patients enrolled
Trial Details
Trial ID
NCT03262480
Start Date
September 1 2017
End Date
December 10 2020
Last Update
December 22 2020
Active Locations (1)
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1
Urology and nephrology center
Al Mansurah, Dakahlia Governorate, Egypt, +2050