Status:

UNKNOWN

Cognitive Training in Patients With MCI Using fMRI

Lead Sponsor:

São Paulo State University

Collaborating Sponsors:

Ricardo Nitrini

Sonia Brucki

Conditions:

Mild Cognitive Impairment

Eligibility:

All Genders

60-90 years

Phase:

NA

Brief Summary

The current project aims to investigate the efficacy of the visual imaging training (VIT) and alphabet search training in comparison to an active control intervention, namely psychoeducation informati...

Detailed Description

We will include 30 subjects with amnestic mild cognitive impairment (MCI) single domain or multiple domain clinical diagnostic, over 60 years old, recruited through the Cognitive and Behavioral Neurol...

Eligibility Criteria

Inclusion

  • Portuguese as native and preferred language; A minimum of 4 years of education; MRI-compatible; Right-handed individuals; Normal corrected vision and hearing; Estimated intelligence average or above (≥ 80 IQ); Amnestic Mild Cognitive Impairment identified by a doctor and neuropsychological tests; Able to give informed consent.

Exclusion

  • History of neurological disorder; History of serious systemic disease; History of severe mental illness; Current untreated alcohol or substance abuse; Medical conditions that compromise in any way the central nervous system; Presence of visual impairment and / or hearing to preclude cognitive testing; Presence of contraindications to MRI exam; Findings in structural MRI that can interfere with the results of the study

Key Trial Info

Start Date :

January 2 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03263247

Start Date

January 2 2017

End Date

December 31 2023

Last Update

May 11 2023

Active Locations (1)

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University of Sao Paulo

São Paulo, São Paulo, Brazil, 05403000