Status:
UNKNOWN
Value of Cabergoline and Low Dose Aspirin in Poor Responders Undergoing ICSI-ET With GnRH Agonist Flare-Up-Protocol
Lead Sponsor:
Cairo University
Conditions:
Invitro Fertilization
Eligibility:
FEMALE
20-39 years
Phase:
PHASE4
Brief Summary
Ovarian stimulation will be done using the Microdose flare-up regimen. The patient will receive diluted doses of the GnRH agonist leuprolide acetate 40 µg, given subcutaneously twice daily. Two days l...
Detailed Description
Ovarian stimulation was done using the Microdose flare-up regimen. The patient received diluted doses of the GnRH agonist leuprolide acetate 40 µg, given subcutaneously twice daily. Two days later, st...
Eligibility Criteria
Inclusion
- Patients with a history of one or more failed IVF cycles with three or less retrieved oocytes
- No age limitation
- Patients with an inadequate ovarian response in previous cycle
- Low estradiol (E2) levels in response to ovarian stimulation in previous cycle
- Lower number of retrieved oocytes in previous trials.
Exclusion
- Severe male factor (azospermia)
- Hydrosalpinx
- History of endometriosis
- Endocrine or metabolic disorders
- Follicle stimulating hormone (FSH) level \> 15 mIU.
- Antimullerian hormone (AMH)\< 0.5 ng/ml
- Any uterine causes of infertility e.g. septate uterus
Key Trial Info
Start Date :
August 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2018
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03263299
Start Date
August 1 2017
End Date
September 1 2018
Last Update
August 28 2017
Active Locations (1)
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1
Kasr Alainy medical school
Cairo, Egypt, 12151