Status:
TERMINATED
Modeling the Neurological Basis and Characterizing the Neurological Phenotype of Obesity Using Human Neural Stem Cells
Lead Sponsor:
University of California, San Diego
Conditions:
Obesity, Morbid
Eligibility:
All Genders
18-90 years
Brief Summary
This study aims to characterize the neurological basis of obesity and response to surgical and medical treatment by inducing adult pluripotent stem cells into neuronal cells from subjects that have de...
Detailed Description
The investigators will consent subjects who have achieved extreme response to either bariatric surgery or pharmacologic treatment for obesity and harvest fibroblasts from skin biopsies, which will be ...
Eligibility Criteria
Inclusion
- History of obesity
- Treatment with bariatric surgery
- Treatment with anti obesity medications
- Greater than 70% excess weight loss at least 6 months after surgery
- Greater than 15% weight loss on anti obesity medications
Exclusion
- Active cancer, not including non-melanoma skin cancer
- Active eating disorder
- Use of anti obesity medications in subjects with a history of bariatric surgery
- Active complication of the upper GI tract in patients with a history of bariatric surgery
Key Trial Info
Start Date :
October 5 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 10 2020
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT03263390
Start Date
October 5 2017
End Date
August 10 2020
Last Update
December 16 2020
Active Locations (1)
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1
University of California San Diego
La Jolla, California, United States, 92037