Status:
COMPLETED
Intraductal Secretin Stimulation Test: What Is the Proper Collection Time?
Lead Sponsor:
Indiana University
Conditions:
Cholangiopancreatography, Endoscopic Retrograde
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim is to evaluate the peak secretory flow rates and bicarbonate concentrations as determined by a 30 minute intraductal secretin stimulation test in patients with a low likelihood of pancreatic p...
Eligibility Criteria
Inclusion
- 1\. Male or female patients ≥ 18 years of age referred to Indiana University Health, University Hospital for ERCP for a biliary indication, at the discretion of the treating MD (e.g. suspected common bile duct stone, initial post-liver transplant evaluation, suspected or confirmed cholangiocarcinoma, suspected primary sclerosing cholangitis -- see exclusion criterion #12)
Exclusion
- Pregnant woman or breast feeding
- Age \<18 years
- Patient unable to give informed consent
- Patient with a history of pancreatic surgery
- Patient with a history of pancreatic cancer
- Patient with a history of acute or chronic pancreatitis
- Patient with radiographic evidence of acute or chronic pancreatitis on CT, MRCP, or EUS
- Patient with a current or prior history of average daily alcohol consumption of greater than 60 g per day for more than 2 years
- Patient with a history of cigarette smoking greater that 20 pack-years
- Patient with a history of pancreas divisum
- Evidence of chronic pancreatitis on pancreatogram during ERCP
- ERCP for an isolated biliary indication with previous biliary sphincterotomy or for biliary stent exchange, when pancreatic entry should easily be avoided by the endoscopist.
- History of allergy or adverse reactions to secretin
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2023
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03263481
Start Date
September 1 2017
End Date
September 1 2023
Last Update
September 22 2023
Active Locations (1)
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1
Indiana University
Indianapolis, Indiana, United States, 46202