Status:

COMPLETED

Impact of the Use of Nandrolone on the Treatment of Malnutrition Induced by Cancer

Lead Sponsor:

Hospital Erasto Gaertner

Conditions:

Cachexia; Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Compare the use of nandrolone associated with corticosteroid for the treatment of cancer-induced malnutrition to treatment with corticosteroids alone in patients with tumors in the high gastro-intesti...

Detailed Description

* Compare muscle mass values obtained before and after the use of anabolic steroids upon assessment by bioelectrical impedance analysis (BIA). * Compare the anabolic effect on quality of life (QLo) of...

Eligibility Criteria

Inclusion

  • Cancer patients above 18 years old.
  • Patients with tumors in the high gastro-intestinal, hepatobiliary and pancreatic tracts in palliation.
  • Patients able to undergo BIA.
  • Malnourished patients as per the subjective global assessment produced by the patient (ASG-PPP) and whose score is greater than nine.
  • Patients who agree to participate in the study.

Exclusion

  • Patients with malignant tumors of other metachronous or synchronous location except nonmelanoma skin tumor
  • Patients with chronic renal failure.
  • Patients on diuretics, recent or chronic.
  • Patients on appetite stimulants and anabolic agents.
  • Patients using pacemakers, which can interfere with the results of BIA

Key Trial Info

Start Date :

February 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2017

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03263520

Start Date

February 1 2016

End Date

October 31 2017

Last Update

February 26 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Erasto Gaertner

Curitiba, Paraná, Brazil, 81520060