Status:
COMPLETED
Cardiac Magnetic Resonance for Asymptomatic Type 2 Diabetics With Cardiovascular High Risk (CATCH) - Pilot Study
Lead Sponsor:
The University of Hong Kong
Collaborating Sponsors:
Radiological Society of North America
Conditions:
Diabetes Mellitus, Type 2
Coronary Artery Disease
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
The aim of this study is to determine the prevalence of myocardial ischaemia in asymptomatic high risk type 2 diabetic patients using stress cardiac MR and how many stress cardiac MR examinations are ...
Detailed Description
Asymptomatic coronary artery disease (CAD) is highly prevalent (ie. 17-59%) in type 2 diabetic patients. In addition, cardiovascular disease remains the most common cause of death in type 2 diabetics....
Eligibility Criteria
Inclusion
- Onset of type 2 diabetes at ≥30yrs old with no history of ketoacidosis
- 60-80yrs old
- Framingham Risk Score ≥20%
Exclusion
- Angina pectoris or chest discomfort
- Stress test or coronary angiography within 2 years
- Previous myocardial infarction (MI)
- Previous coronary artery stenting or coronary artery bypass grafting
- Any clinical indication or contraindication for stress testing
- Any contraindication to stress CMR (eg. non-MRI compatible devices)
- Contraindication to gadolinium based contrast agent (eg. Renal impairment with an estimated glomerular filtration rate (GFR) \<30ml/min/1.73m2)
- Life expectancy \<2 years due to cancer or liver disease
- Contraindication to dual antiplatelet therapy
- Planned need for concomitant cardiac surgery
- Refusal or inability to sign an informed consent.
- Potential for non-compliance towards the requirements in the trial protocol
- Unable to cover the costs of percutaneous coronary intervention (PCI) whether through government subsidies, etc
Key Trial Info
Start Date :
August 10 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 29 2019
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT03263728
Start Date
August 10 2017
End Date
January 29 2019
Last Update
August 20 2019
Active Locations (1)
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1
The University of Hong Kong
Hong Kong, Hong Kong