Status:

COMPLETED

Pretreatment Staging of High-Risk Prostate Cancer With 18F-Fluciclovine PET/MRI

Lead Sponsor:

University of Alabama at Birmingham

Conditions:

Prostate Cancer

Eligibility:

MALE

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

There is great need for improved preoperative imaging in men with high-risk prostate cancer. Investigators propose to develop and validate an optimized simultaneous PET/MRI protocol for local, regiona...

Eligibility Criteria

Inclusion

  • \- High-risk biopsy-proven treatment-naïve prostate adenocarcinoma (Gleason score ≥ 8 and/or serum PSA \> 20)

Exclusion

  • Inability to tolerate or undergo PET/MRI
  • Previous or current hematologic or lymphatic disorder (including leukemia, lymphoma, Castleman's disease, etc.)
  • Recurrent prostate adenocarcinoma
  • Known visceral, osseous, or extrapelvic metastases prior to fluciclovine-PET/MRI
  • Known allergy to glucagon or gadolinium-based contrast

Key Trial Info

Start Date :

November 8 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 13 2020

Estimated Enrollment :

18 Patients enrolled

Trial Details

Trial ID

NCT03264456

Start Date

November 8 2017

End Date

February 13 2020

Last Update

March 9 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Alabama at Birmingham Medical Center

Birmingham, Alabama, United States, 35249