Status:

COMPLETED

Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain

Lead Sponsor:

Jawaharlal Nehru Medical College

Conditions:

Ropivacaine

Laparoscopic Cholecystectomy

Eligibility:

All Genders

15-80 years

Phase:

PHASE4

Brief Summary

Pain still remains a limiting factor in early discharge of patients undergoing laparoscopic cholecystectomy. Almost all earlier studies done to compare the efficacy of local anaesthetics used intraper...

Detailed Description

Aims \& Objectives: To conduct a randomized, triple-blind, placebo-controlled study by standardizing dose of local anesthetic, to compare the effectiveness of intraperitoneal against intraincisional u...

Eligibility Criteria

Inclusion

  • All patients in the age group of 15-80 years
  • Patients conferring to Grade I or II of American Society of Anesthesiologists (ASA) physical status classification system only
  • Patients undergoing elective Laparoscopic Cholecystectomy
  • Patients having symptomatic cholelithiasis only
  • Patients operated by a single surgeon were included.

Exclusion

  • Patients with known allergic reactions to local anesthetics
  • Cases that were converted to open cholecystectomy
  • Patients with major intra-operative complications
  • Patients suffering from acute cholecystitis, empyema or malignancy of gall bladder, having history of chronic pain or those taking frequent analgesics or opioids pre-operatively
  • Patients with peptic ulceration, bleeding disorders, impaired renal and/or hepatic function, and sensitivity to NSAIDs or opioids.
  • Patients in whom gall bladder (GB) stones are found incidentally on ultrasonography (USG) (asymptomatic cholelithiasis)
  • Patients suffering from severe chronic medical diseases and morbid obesity
  • Patients unable to comprehend instructions or having communication problems were excluded from the study.

Key Trial Info

Start Date :

April 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 15 2017

Estimated Enrollment :

353 Patients enrolled

Trial Details

Trial ID

NCT03265223

Start Date

April 1 2014

End Date

August 15 2017

Last Update

August 30 2017

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Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain | DecenTrialz