Status:
COMPLETED
Skin Ageing Signatures and Cancer
Lead Sponsor:
Queen Mary University of London
Collaborating Sponsors:
University of Edinburgh
Conditions:
Skin Cancer
Eligibility:
FEMALE
55-65 years
Brief Summary
The aim of this study is to identify genetic patterns in normal ageing skin in order to better understand age-related changes. Data has suggested that skin ageing has a genetic basis and past studies...
Detailed Description
This study will use new tools in an attempt to understand the small changes that take place in skin and may be linked to skin ageing either due to age or the effect of the sun. Some data suggests that...
Eligibility Criteria
Inclusion
- Able to give written informed consent prior to admission to this study.
- Female aged between 55 and 65 years.
- Willing and able to comply with clinical/photographic assessment and laboratory tests
Exclusion
- Previous history of skin cancer, active inflammatory or other skin condition that in the opinion of the investigator may affect the skin ageing assessment.
- Feverish symptoms which lasted for ≥48 hours prior to study entry.
- Currently suffering from or having suffered during the last month, with any common systemic disease except arterial hypertension.
- Received any of the following treatment for more than 6 months during the last two years: hypo or hyperthyroidism treatment, corticoids, non-steroids anti-inflammatory, antihistamines, immunosuppressive treatments, diuretics, antibiotics, anticoagulants, beta blockers.
- Currently experiencing or having experienced in the last two months prior to study entry problems affecting the skin of the face or forearm for instance acne, eczema, psoriasis, seborroheic dermatitis, herpes zoster.
- Currently receiving or having received in the last two months prior to study entry any of the following dermatological treatments for more than 8 days: hormone based cream, retinoid based facial cream, \> 8% concentration alpha hydroxy acid based cream, topical steroids, antibiotics and antifungals
- Previous facial aesthetic treatments such as: lifting, chemical peeling, dermabrasion, electrocoagulation, laser, sclerotherapy, reconstructive surgery, botox injection, filler injection.
- Currently using a hormone based cream that is applied on the forearm for hormonal replacement therapy.
- Have had a change in skin colour during within one month prior to study entry due to sun exposure
- Had a session of UV therapy for treatment purposes or in a beauty salon within one month prior to study entry.
- Use of a self-tanning product
Key Trial Info
Start Date :
June 2 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 22 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03265678
Start Date
June 2 2017
End Date
January 22 2018
Last Update
April 23 2024
Active Locations (1)
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1
Barts Health NHS Trust
London, United Kingdom, E1 1BB