Status:

TERMINATED

Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery

Lead Sponsor:

University of Calgary

Conditions:

Probiotics

Infant, Newborn

Eligibility:

All Genders

Phase:

NA

Brief Summary

Congenital defects of the gastrointestinal tract commonly require surgical intervention in the neonatal period. Intestinal surgery during this critical period of microbiome acquisition results in aber...

Detailed Description

Research Objectives/Question: The main objective of this study is to determine the impact of probiotics administration on the intestinal microbiome in neonates undergoing gastrointestinal surgery. P...

Eligibility Criteria

Inclusion

  • Infants born between 23 - 41 weeks of gestation
  • Required gastrointestinal surgery (including spontaneous intestinal perforation, bowel atresia, mechanical bowel obstruction, volvulus, gastroschisis)
  • Ready to start enteral feeding

Exclusion

  • Infants with major congenital anomalies excluding gastrointestinal tract
  • Palliative care patients
  • 4\. Septic babies with positive blood, CSF or urine culture

Key Trial Info

Start Date :

December 3 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 15 2024

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT03266315

Start Date

December 3 2022

End Date

July 15 2024

Last Update

July 18 2024

Active Locations (1)

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1

University of Calgary

Calgary, Alberta, Canada, T3M1M4