Status:

COMPLETED

Changes of the Corneal Endothelial Cell Count After Artisan Phakic Intraocular Lens Implantation

Lead Sponsor:

Assiut University

Conditions:

High Myopia

Eligibility:

All Genders

20+ years

Brief Summary

the investigator will evaluate the change in endothelial cell count in eyes implanted with the iris-claw phakic Artisan lens for treatment of moderate to high myopia using specular microscopy

Detailed Description

Iris-fixated phakic intraocular lenses (pIOLs) are used worldwide to correct high myopia, hyperopia, and astigmatism. It is used to correct high degrees of myopia in patients for whom laser excimer re...

Eligibility Criteria

Inclusion

  • an age greater than 20 years, stable myopia with a variation in spherical equivalent of less than -0.50 diopter (D) during the 12 month preoperative period, a normal anterior segment with an ACD (i.e., the area between the corneal endothelium and the central anterior lens capsule) greater than 3.00 mm, an endothelial cell count of 2000 cells/mm2 or greater, no corneal, pupil, or iris abnormalities; and no history of glaucoma and chronic or recurrent uveitis , having contraindications to laser in situ keratomileusis based on pachymetric data or other corneal shape characteristics, and an intraocular pressure of 20 mm Hg or less.

Exclusion

  • an ACD less than 3.0 mm, history of ocular surgery, glaucoma, chronic uveitis, or preexisting ocular pathologic features or abnormalities.

Key Trial Info

Start Date :

October 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2020

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT03266354

Start Date

October 1 2017

End Date

January 1 2020

Last Update

January 20 2021

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Fculty of medicine, Assiut university

Asyut, Egypt