Status:
UNKNOWN
Role of Anti-platelet in Treatment of Acute Ischemic Stroke
Lead Sponsor:
Assiut University
Conditions:
Stroke
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Role of anti-platelet in treatment of acute ischemic stroke to determine the safety of immediate anti-platelet therapy .that is started as soon as possible within the first 24 hours of the onset of sy...
Detailed Description
In 2015, stroke was the second most frequent cause of death after coronary artery disease, accounting for 6.3 million deaths (11% of the total).Studies have reported a 30-day recurrence rate of 1.1 to...
Eligibility Criteria
Inclusion
- Age of the patients is 40 years or older.
- Patients not eligible for recombinant tissue plasminogen activator or any other acute reperfusion therapy presenting after 6hours of onset of symptoms.
- Patients presented with clinical symptoms of acute stroke or TIA with onset less than 24 hours before starting any treatment.
- The diagnosis of stroke or TIA basing on clinical examination using National Institute of Health stroke scale (NIHSS) by a stroke specialist
Exclusion
- Any history of ICH or systemic hemorrhage.
- Any evidence of hemorrhage on baseline CT brain imaging.
- Patients presented with failed medical or surgical thrombectomy.
- International normalized ratio (INR) more than 1.5.
- History of allergy to aspirin or clopidogrel or both of them.
- Platelets count less than 100,000/mm3.
- Hematocrit less than 30 mg/dL .
- glucose less than 50 mg/dL or greater than 400 mg/dL.to exclude hypoglycemia induced focal neurological deficit.
Key Trial Info
Start Date :
January 4 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 4 2020
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03266731
Start Date
January 4 2018
End Date
January 4 2020
Last Update
August 31 2017
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