Status:

UNKNOWN

Vietnam Cryptococcal Retention in Care Study - Version 2.1

Lead Sponsor:

National Hospital for Tropical Diseases, Hanoi, Vietnam

Collaborating Sponsors:

Centers for Disease Control and Prevention

Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Conditions:

HIV/AIDS

Cryptococcal Meningitis

Eligibility:

All Genders

18+ years

Brief Summary

This is a multicenter prospective cohort evaluation of the implementation of a cryptococcal antigen (CrAg) screening program at selected outpatient HIV clinics (OPCs) and network laboratories in Vietn...

Detailed Description

The project will be implemented in 2 phases; Phase 1: From August 2015 to March 2017 \[projected\], HIV-infected patients who present for HIV care and undergo CD4 testing will be reviewed to determine...

Eligibility Criteria

Inclusion

  • Aged ≥ 18 years (having passed 18th birthday using Western calendar)
  • Confirmed HIV infection using National Testing Algorithm
  • CD4 ≤100 cells/μL
  • Able to provide written informed consent
  • Enrolled at and plan to receive ongoing outpatient care at one of the selected study OPCs

Exclusion

  • History of prior CM
  • Receipt of systemic antifungal medication for more than 4 consecutive weeks within the past 6 months
  • Receipt of ART for more than 4 consecutive weeks within the past year
  • For CrAg-positive patients only: Known to be currently pregnant or planning to become pregnant during the study period

Key Trial Info

Start Date :

August 14 2015

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 31 2018

Estimated Enrollment :

1184 Patients enrolled

Trial Details

Trial ID

NCT03267407

Start Date

August 14 2015

End Date

March 31 2018

Last Update

September 12 2017

Active Locations (1)

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National Hospital for Tropical Diseases

Hanoi, Vietnam, 100000