Status:

UNKNOWN

Neuropsychiatric Adverse Effects in Patients With Chronic Hepatitis C Treated by Direct Acting Antiviral Drugs

Lead Sponsor:

Assiut University

Conditions:

Hepatitis C

Eligibility:

All Genders

Brief Summary

Neuropsychiatric adverse effects of direct acting antiviral drugs, especially Sofosbuvir and Daclatasvir combination therapy (with or without ribavirin) in patients with chronic hepatitis C , genotype...

Detailed Description

Treatment of hepatitis C virus, a virus infecting over one hundred seventy million worldwide, has evolved over the last two decades and moved from interferon-alpha monotherapy to pegylated interferon-...

Eligibility Criteria

Inclusion

  • Patients with chronic hepatitis C only will be included.
  • Patients who are eligible for treatment by DAAs only.

Exclusion

  • Cirrhotic patients will be excluded based on USS, APRI score index and FIB4 index.
  • Hepatitis B infected patients will also be excluded.
  • Patients with current or previous history of neuropsychiatric disorders will be excluded.
  • Failure to obtain consent.

Key Trial Info

Start Date :

January 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2020

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03268317

Start Date

January 1 2018

End Date

January 1 2020

Last Update

August 31 2017

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