Status:

COMPLETED

Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in OSAS

Lead Sponsor:

Bezmialem Vakif University

Conditions:

Periodontitis

Obstructive Sleep Apnea

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The main objective of this study is to compare the effect of the non-surgical periodontal treatment on serum and saliva oxidative stress parameters in patients with periodontitis and obstructive sleep...

Detailed Description

There is evidence supporting that OSAS is an independent risk factor for cardiovascular and cerebrovascular diseases such as hypertension, congestive heart failure, myocardial infarction, cardiac-arrh...

Eligibility Criteria

Inclusion

  • aged ≥18 years old
  • having more than 16 teeth
  • BMI\>25 kg/m2

Exclusion

  • patients with a history of diabetes mellitus or respiratory diseases
  • patients who were under any medication that was known to influence periodontal tissues
  • patients with a history of any periodontal treatment in the past 6 months
  • patients with hormonal changes such as pregnancy or lactation; and 5) patients having fixed dentures or removable prothesis
  • OSAS treatment started (using OSAS therapy device or undergoing surgical operation)

Key Trial Info

Start Date :

July 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2023

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03268473

Start Date

July 1 2017

End Date

November 1 2023

Last Update

February 28 2024

Active Locations (1)

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1

Bezmialem Vakıf University, Faculty of Dentistry, Deparment of Periodontology,

Istanbul, Turkey (Türkiye), 34093