Status:

RECRUITING

Computational Drug Repurposing for All EBS Cases

Lead Sponsor:

Joyce Teng

Conditions:

Epidermolysis Bullosa

Healthy

Eligibility:

All Genders

Brief Summary

The study will compare gene expression differences between blistered and non-blistered skin from individuals with all subtypes of EB, as well as normal skin from non-EB subjects. State of the art comp...

Detailed Description

Although gene, cell, and protein-based therapies are in development for patients suffering from all subtypes of epidermolysis bullosa (EB), new pharmacological treatments are in dire need. Characteriz...

Eligibility Criteria

Inclusion

  • Subjects of all ages
  • Diagnosis of all subtypes of EB subjects
  • Healthy, non-EB subjects
  • Ability to complete study visit to collect tissue and blood specimen

Exclusion

  • Pregnancy, breast feeding
  • Prior history of liver disease
  • Serious known concurrent medical illness or infection, which could potentially present a safety risk and/or prevent tissue collection from subjects

Key Trial Info

Start Date :

November 28 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03269474

Start Date

November 28 2017

End Date

December 31 2024

Last Update

February 13 2024

Active Locations (1)

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Pediatric Dermatology Clinic at Stanford Children's Hospital

Palo Alto, California, United States, 94304