Status:
COMPLETED
Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery
Lead Sponsor:
University of Manitoba
Conditions:
Pain, Postoperative
Shoulder Joint Disorder
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
In this single-centre, double-blinded, randomized controlled superiority trial, 189 participants having outpatient, arthroscopic shoulder surgery will be randomized into 3 equal sized groups. All part...
Detailed Description
BACKGROUND \& RATIONALE Optimal postoperative analgesia is very important in the ambulatory arthroscopic shoulder surgery patient population; interscalene blocks are used for this surgery because they...
Eligibility Criteria
Inclusion
- Elective ambulatory surgery patients undergoing arthroscopic shoulder surgery
- Including rotator cuff repair
- Stabilization procedures
- Acromioplasty
- Debridement and distal clavicle excision
Exclusion
- Patient refusal
- Diabetes
- Pregnancy
- Coagulopathy significant enough to be a contraindication to regional anesthesia as determined by the attending anesthesiologist
- Sensitivity to local anesthetics, dexamethasone or dexmedetomidine
- Severe chronic obstructive pulmonary disease
- Contralateral vocal cord paralysis
- Contralateral diaphragmatic paralysis
- Surgical limb brachial plexus neuropathy
- Interscalene block site infection
- Systemic glucocorticoids in the last 2 weeks
- Epidural or intraarticular steroid injection in the past 3 months
- Chronic opioid use defined as daily use for the last two weeks
- Active peptic ulcer disease
- End-stage renal disease
- Cirrhotic liver disease
- Ventricular dysfunction
- Advanced heart block
- Previous participation in the study.
Key Trial Info
Start Date :
September 18 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 13 2018
Estimated Enrollment :
198 Patients enrolled
Trial Details
Trial ID
NCT03270033
Start Date
September 18 2017
End Date
October 13 2018
Last Update
April 16 2019
Active Locations (1)
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1
Pan Am Surgical Centre
Winnipeg, Manitoba, Canada, R3M 3E4