Status:
UNKNOWN
Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis
Lead Sponsor:
University of Health Sciences Lahore
Conditions:
Chronic Periodontitis
Eligibility:
All Genders
19-40 years
Phase:
PHASE2
Brief Summary
Periodontitis is an infectious inflammatory disease affecting the periodontal tissue (Gingivae, alveolar bone, periodontal ligament and cementum). Chronic Periodontitis is considered to be the most pr...
Detailed Description
Periodontal disease is one of the most common diseases in humans and is responsible for most of the tooth loss in adults. World health Organisation report of 2005 described that the global problem per...
Eligibility Criteria
Inclusion
- Male and female healthy individual
- Individuals diagnosed with chronic periodontitis according to the WHO criteria.
- Age 19 to 40 years.
Exclusion
- Patients with gingivitis only.
- Patients using tobacco products and alcohol.
- Underlying systemic pathology such as diabetes mellitus, cardiovascular disease, arthritis etc.
- Oral mucosal pre-neoplastic lesions (leukoplakia, erthroplakia, lichen planus) and oral carcinomas.
- Obese patients.
- Pregnant females.
- Xerostomia.
- Previous history of radiotherapy or chemotherapy.
- Positive history of oral prophylactic procedures (mouthwashes and antibiotics).
- Positive history of any periodontal treatment during last 6 months.
- Positive antibiotic therapy history within last month of study.
Key Trial Info
Start Date :
September 11 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 11 2018
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03270280
Start Date
September 11 2017
End Date
April 11 2018
Last Update
September 1 2017
Active Locations (1)
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1
Fatima Memorial Hospital
Lahore, Punjab Province, Pakistan, 0092