Status:
COMPLETED
Pharmacogenomic Testing in Primary Care
Lead Sponsor:
University of Michigan
Conditions:
Antidepressants Causing Adverse Effects in Therapeutic Use
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a 6-month randomized, wait-listed, controlled pilot trial conducted in 6 department of family medicine (DFM) clinics at the University of Michigan (UM). Physicians practicing at a UM DFM clini...
Detailed Description
This is a 6-month randomized, wait-listed, controlled pilot trial conducted in 6 department of family medicine (DFM) clinics at the University of Michigan (UM). We will enroll physicians practicing at...
Eligibility Criteria
Inclusion
- Physician participants
- Inclusion criteria:
- Be a practicing physician at a University of Michigan Department of Family Medicine clinic
- Be willing to use PGx test results for their patients enrolled in the study
- Be willing to allow study staff to contact their patients
- Self-report that they are willing to prescribe antidepressants
- Exclusion criteria:
- Do not meet inclusion criteria
- Patient Participants
- Inclusion:
- Be a patient of a participating physician
- Have a new prescription for one of the following antidepressant medications: citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Prozac Weekly, Rapiflux, Sarafem, Selfemra), fluvoxamine (Luvox, Luvox CR), paroxetine (Paxil, Paxil CR), sertraline (Zoloft), duloxetine (Cymbalta, Irenka), venlafaxine (Effexor), venlafaxine XR (Effexor XR), nortriptyline (Aventyl, Pamelor), bupropion (Forfivo XL, Wellbutrin, Wellbutrin SR, Wellbutrin XL), mirtazapine (Remeron, Remeron Soltab), or vortioxetine (Trintellix)
- Be willing to undergo PGx testing via single tube blood draw
- Exclusion:
- Do not speak English
- Have previously undergone PGx testing
- Are unable to provide their own consent to participate in the study
- Have been taking the new antidepressant prescription for longer than 4 weeks (prior to screening)
Exclusion
Key Trial Info
Start Date :
December 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 6 2022
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT03270891
Start Date
December 1 2017
End Date
May 6 2022
Last Update
April 11 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Michigan
Ann Arbor, Michigan, United States, 48109