Status:

COMPLETED

Serum Progesterone on the Day of Embryo Transfer and Pregnancy Rate.

Lead Sponsor:

Instituto Valenciano de Infertilidad, IVI VALENCIA

Conditions:

Ongoing Pregnancy Rate

Eligibility:

FEMALE

18-50 years

Brief Summary

This study aims to analyze whether serum Progsterone levels on the day of Embryo Transfer are related with Ongoing Pregnancy rate in artificial endometrial preparation cycles with intravaginal microni...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Age \<50 years old
  • Hormonal Replacement therapy cycle for embryo transfer in any of the following situations:
  • Embryos in fresh cycle with donated oocytes.
  • Subsequent embryo transfers of vitrified embryos in cycles of donated oocytes.
  • Frozen embryo transfers in cycles with autologous oocytes.
  • Endometrial line: \>6.5-7mm (with trilaminar aspect) in proliferative phase, before introducing progesterone.
  • Administration of natural micronized progesterone intravaginally (400 mg/12 hours for 5 complete days (10 dosis), before the embryo transfer and maintained until pregnancy week 12.
  • Embryo transfer of blastocyst (day 5-6).
  • Signed Informed Consent
  • Exclusion Criteria
  • Uterine pathology (submucous o intramural fibroids (\>4 cm) or which deform the uterine cavity; endometrial polyps or Müllerian anomalies; or adnexal anomalies (communicating hydrosalpinx).
  • Simultaneous participation in another clinical study.
  • Participation in another clinical study before the inclusion in the present study, and which could affect the objectives of the present study.

Exclusion

    Key Trial Info

    Start Date :

    September 8 2017

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    November 28 2018

    Estimated Enrollment :

    1205 Patients enrolled

    Trial Details

    Trial ID

    NCT03272412

    Start Date

    September 8 2017

    End Date

    November 28 2018

    Last Update

    January 31 2019

    Active Locations (1)

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    Instituto Valenciano de Infertilidad Spain

    Valencia, Spain, 46015