Status:
RECRUITING
Clinical Characteristics of Asthma and COPD Overlap for Patients With Asthma and COPD in Hong Kong
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
COPD
Asthma
Eligibility:
All Genders
18+ years
Brief Summary
This study is to assess the prevalence of Asthma COPD Overlap in subjects with diagnosed asthma and chronic obstructive pulmonary disease (COPD). The subsequent morbidity and mortality of subjects wil...
Detailed Description
Rationale: Around 15 to 20% of COPD patients have features of asthma. These patients have more frequent and more severe exacerbations, and higher medical utilization. The Global Initiative for Asthma...
Eligibility Criteria
Inclusion
- Subjects must fulfil all of the following criteria:
- All patients with confirmed diagnosis of COPD (post-bronchodilator FEV1/FVC\<0.7 based on the medical records) 1 or asthma (defined as those with a consistent history and prior documented evidence of variable airflow obstruction, with evidence of an increase in FEV1 greater than 12% or 400 mL following bronchodilator or bronchial hyperresponsiveness on bronchial provocation testing, when stable) 6
- Aged \>40 years old
- Signed written informed consent to participate in the study
Exclusion
- Patients currently with acute exacerbation of COPD by GOLD definition (any worsening of a patient's respiratory symptoms that is beyond normal day-to-day variations and requires a change in medication) 1 or acute exacerbation of asthma by GINA guideline. 6
- Patients with respiratory diseases that can show similar symptoms to chronic airway diseases such as bronchiectasis, tuberculosis (TB)-destroyed lung parenchyma, endobronchial TB, and lung cancer, or those who have history of these diseases based on physician's judgment
- Patients currently diagnosed with pneumonia and acute bronchitis
- Patients currently randomized in other clinical studies
Key Trial Info
Start Date :
September 15 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
1600 Patients enrolled
Trial Details
Trial ID
NCT03272932
Start Date
September 15 2017
End Date
December 30 2025
Last Update
August 21 2024
Active Locations (1)
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1
Prince of Wales Hospital
Hong Kong, Hong Kong