Status:
COMPLETED
The Effect of Proton Pump Inhibition on Palpitations
Lead Sponsor:
Jordan Collaborating Cardiology Group
Collaborating Sponsors:
University of Jordan
Conditions:
Arrhythmia
Eligibility:
All Genders
16-99 years
Phase:
PHASE4
Brief Summary
Feeling of palpitations with no clear arrhythmia is frequently encountered in clinical practice. The majority of these patients have documented sinus rhythm even while having symptoms. Gastrointestina...
Detailed Description
One hundred and fifty patients with palpitations and no clear cause for their symptoms will be randomized to receive either proton pump inhibitor (PPI) (lanzoprazole 30 mg) or placebo for one month. A...
Eligibility Criteria
Inclusion
- Persons with palpitations and no clear cause who are above the age of 16 years and who consent to the study will be included
- Clear causes that should be excluded are true arrhythmia such SVT or VT or frequent premature atrial or ventricular contractions or any organic cause such as thyroid disorder, anemia (hg less than 11 g/dl) and obvious anxiety disorder
- Arrhythmia can be excluded by an ECG showing sinus rhythm or sinus tachycardia during episodes or measurement of heart rate by a reliable method during symptoms showing regular heart rate less than 120 beats per minute.
Exclusion
- Refusal to sign consent form
- Already taking PPI or H2 blocker
- Frequency of symptoms less than 2 times per week
Key Trial Info
Start Date :
May 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT03273634
Start Date
May 20 2017
End Date
June 1 2018
Last Update
August 8 2018
Active Locations (1)
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1
The University of Jordan
Amman, Jordan, 11942