Status:

UNKNOWN

Vascular and Metabolic Changes in Postmenopausal Diabetics

Lead Sponsor:

Assiut University

Conditions:

Diabete Type 2

Eligibility:

FEMALE

50-70 years

Brief Summary

The presence of type 2 diabetes mellitus (T2DM) also increases the relative risk of developing cardiovascular disease in women compared to men. Carotid intima media thickness (IMTc) was increased with...

Detailed Description

Introduction Complications of diabetes, such as cardiovascular disease, are associated with increased mortality among type 2 diabetes mellitus patients. The presence of type 2 diabetes mellitus (T2DM)...

Eligibility Criteria

Inclusion

  • post-menopausal women
  • aged 50-70 years
  • amenorrhea for over 24 months.
  • The diabetic participants will receive their treatment for T2DM (oral hypoglycemic agents or insulin).

Exclusion

  • Patients receiving hormone replacement therapy.
  • History of abnormal vaginal bleeding.
  • Patients receiving vitamin B12, vitamin D and folic acid regularly.
  • History of malignancy or neurological diseases as epilepsy, parkinsonism and Alzheimer disease.
  • Antifolate medications as methotrexate are excluded from the study.

Key Trial Info

Start Date :

October 2 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 15 2018

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03273738

Start Date

October 2 2018

End Date

November 15 2018

Last Update

June 27 2018

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