Status:

COMPLETED

The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke

Lead Sponsor:

University of Manchester

Collaborating Sponsors:

Medical Research Council

University of Nottingham

Conditions:

Oropharyngeal Dysphagia

Stroke

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The study is designed to explore the effectiveness of non-invasive cerebellar stimulation to enhance motor plasticity in the cortex after stroke. The investigators have shown that the human cerebellum...

Detailed Description

Protocols: Hypothesis 1: Cortical excitability (in both dominant and non-dominant swallowing cortex) to TMS and swallowing behaviour assessed with a swallowing reaction time task will be measured at...

Eligibility Criteria

Inclusion

  • Patients aged 18 years and over
  • All patients with an acute anterior or posterior cerebral circulation stroke within 6 weeks of symptom onset.

Exclusion

  • Advanced dementia
  • Previous history of dysphagia
  • Patients judged to be clinically unstable
  • Presence of implanted cardiac pacemaker or defibrillator
  • Any severe chronic medical condition that compromises cardiac or respiratory status
  • Patients with acute lower respiratory tract infections requiring antibiotic treatment.

Key Trial Info

Start Date :

January 14 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2022

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT03274947

Start Date

January 14 2019

End Date

October 31 2022

Last Update

December 1 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Upper G.I laboratory, Salford Royal Hospital

Manchester, Greater Manchester, United Kingdom, M6 8HD

2

Stroke Unit, Nottingham University Hospitals

Nottingham, Notthinghamshire, United Kingdom