Status:

ACTIVE_NOT_RECRUITING

Pathophysiology and Risk of Atrial Fibrillation Detected After Ischemic Stroke

Lead Sponsor:

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Collaborating Sponsors:

Western University, Canada

London Health Sciences Centre

Conditions:

Stroke, Ischemic

Transient Ischemic Attack

Eligibility:

All Genders

18+ years

Brief Summary

This prospective non-interventional cohort study investigates the pathophysiology of Atrial Fibrillation Detected After Stroke or transient ischemic attack (AFDAS) by comparing the autonomic function ...

Detailed Description

This study enrolls patients with acute ischemic stroke at the London Health Sciences Center in London, Ontario, Canada. The heart rhythm of the patients is monitored with a CardioSTAT® Holter device (...

Eligibility Criteria

Inclusion

  • MCA territory-transient ischemic attack or -acute ischemic stroke patients seen in the Emergency Department or admitted to University Hospital, London, Ontario, Canada
  • Age ≥ 18 years old
  • Patient or Substitute Decision Maker must give written informed consent

Exclusion

  • Patients with autonomic dysfunction such as Parkinson's disease that can be interfering with outcome assessment based on qualified investigator's judgment.
  • Patients taking tricyclic antidepressant (TCAs)
  • Patients in whom the acute stroke is primarily hemorrhagic
  • Patients with both TIA and atrial fibrillation
  • Patients with both TIA and large vessel disease
  • Patients with inflammatory diseases

Key Trial Info

Start Date :

April 18 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 7 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03275155

Start Date

April 18 2017

End Date

May 7 2026

Last Update

April 1 2025

Active Locations (1)

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1

University Hospital, London Helath Sciences Center

London, Ontario, Canada, N6A 5A5