Status:
COMPLETED
Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Cannabis Use
Cognitive Change
Eligibility:
All Genders
10-19 years
Phase:
NA
Brief Summary
This study will use a randomized controlled design to test whether 30 days of cannabis abstinence, compared to 30 days of monitoring, is associated with improvements in cognitive functioning. Non-usin...
Detailed Description
This is a 5-year randomized, longitudinal trial of cannabis abstinence designed to determine (1) if performance improves with abstinence beyond that observed with continued cannabis use, and if so, (2...
Eligibility Criteria
Inclusion
- General Inclusion Criteria for School-Aged Study Component:
- Male and female adolescents from the Boston area who are between the ages of 10 and 19 (inclusive);
- Have a parent or legal guardian who is able and willing to provide written informed consent for the active study phase (if under the age of 18);
- Competent and willing to provide written informed assent for the active study phase (if under the age of 18);
- Competent and able to provide written informed consent (if age 18 or older)
- Able to communicate in English language
- Able to commit to 9 study visits in approximately 60 days
- No severe developmental delays (including, but not limited to, Autism Spectrum Disorder, Intellectual Disability, and Down Syndrome)
- Able to safely participate in the protocol and appropriate for outpatient level of care
- Cannabis-Using Group Inclusion Criteria:
- Use of cannabis at least once per week on most weeks
- Cannabis use reported within 7 days of both baseline visits
- No immediate plan to discontinue cannabis use
- Non-Using Group Inclusion Criteria:
- Use of cannabis less than 5 times in lifetime
- No cannabis use in the past year
- No cannabis use before age 16
- Exclusion Criteria for School-Aged Study Component
- \- Passive consent for initial school-wide assessment withdrawn by parent or legal guardian or written parental consent not provided prior to screening
Exclusion
Key Trial Info
Start Date :
August 7 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 9 2022
Estimated Enrollment :
201 Patients enrolled
Trial Details
Trial ID
NCT03276221
Start Date
August 7 2017
End Date
November 9 2022
Last Update
February 1 2024
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114