Status:
COMPLETED
Dexmedetomidine Combined With Lidocaine Infusion Affect Inflammation Cytokines
Lead Sponsor:
Anqing Municipal Hospital
Collaborating Sponsors:
The First Affiliated Hospital of Anhui Medical University
Conditions:
Anesthesia; Reaction
Eligibility:
FEMALE
40-65 years
Phase:
NA
Brief Summary
Objective: The present study was to evaluate the effects of dexmedetomidine alone, lidocaine alone and their combined infusion on postoperative inflammation cytokines after Laparoscopic hysterectomy. ...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists (ASA) physical status I and II
- weighted 50 kg-65 kg
- aged 40-65 yr
- elective laparoscopic hysterectomy with general anesthesia
Exclusion
- a history of allergy to local anesthetics
- severe respiratory, renal or hepatic disease
- preoperative opioids medication
- psychiatric medical history
- Patients with severe hypotension \[mean arterial pressure (MAP\<60 mmHg)\] or bradycardia \[heart rate (HR) \<40 beats per minute (bpm)\], arrhythmia, or urticaria due to lidocaine and dexmedetomidine infusion during the surgery
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 10 2020
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT03276533
Start Date
November 1 2017
End Date
August 10 2020
Last Update
March 10 2022
Active Locations (1)
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1
Department of Anqing Hospital Anesthesiology
Anqing, Anhui, China, 246000