Status:
UNKNOWN
Uterus Transplantation From Live Donors and From Deceased Donors - Clinical Study
Lead Sponsor:
Institute for Clinical and Experimental Medicine
Collaborating Sponsors:
University Hospital, Motol
Sahlgrenska University Hospital
Conditions:
Mayer Rokitansky Kuster Hauser Syndrome
Mullerian Aplasia
Eligibility:
FEMALE
18-60 years
Phase:
PHASE3
Brief Summary
Uterus transplantation (UTx) is the only causative treatment for congenital or acquired uterus absence. Individual cases of UTx from a live donor (LD UTx) with healthy child birth performed so far sho...
Detailed Description
Introduction: Uterus transplantation (UTx) is the only causative treatment for congenital or acquired uterus absence, i.e. absolute uterine factor infertility (AUFI). Feasibility of uterus transplanta...
Eligibility Criteria
Inclusion
- Inclusion Criteria for UTx recipient:
- 18 - 40 years of age
- good general health
- congenital or acquired uterus absence
- desire for a child
- Exclusion Criteria for UTx recipient:
- age over 40
- serious comorbidity
- Inclusion Criteria for a live uterus donor:
- female
- 18 - 60 years of age
- maximum 4 child births
- maximum 1 Cesarian section
- good general health
- Exclusion Criteria for a live uterus donor:
- age over 60
- hypertension with organ damage
- diabetes mellitus
- other serious comorbidity
- Inclusion Criteria for a deceased brain-dead uterus donor:
- female
- age under 60
- no previous hysterectomy
- no previous uterus malignancy
Exclusion
Key Trial Info
Start Date :
October 9 2015
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03277430
Start Date
October 9 2015
End Date
December 31 2025
Last Update
February 27 2019
Active Locations (1)
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1
Institute for Clinical and Experimental Medicine
Prague, Czechia, 14021