Status:
UNKNOWN
Effect of Orthoses and Underfoot Vibration on Balance in Neuropathy
Lead Sponsor:
St George's, University of London
Collaborating Sponsors:
University College London Hospitals
Conditions:
CMT - Charcot-Marie-Tooth Disease
Peripheral Neuropathy
Eligibility:
All Genders
18+ years
Brief Summary
A cross-sectional study which will look at the effects of AFO's and vibrating insoles on balance performance in people with CMT disease.
Detailed Description
Balance impairments and falls are more common in people who have Charcot Marie Tooth disease (CMT) than in people without the condition. CMT is a condition which affects the nerves causing a variety o...
Eligibility Criteria
Inclusion
- Clinical or genetically confirmed diagnosis of CMT or related peripheral neuropathy
- Mixed sensory and motor presentation
- Over 18 years
- Able to stand unsupported for five minutes
- Able to walk for 50m with or without a walking stick or orthotic devices
Exclusion
- Presence of other significant neurological disorders (such as multiple sclerosis, cerebrovascular diseases, epilepsy, movement disorders), or major comorbidities (e.g. vestibular dysfunction, use of medication which may affect balance, cognitive impairment, presence of medical conditions in which exercise training may be detrimental).
- Presence of peripheral neuropathy caused by a condition other than CMT.
- Limb surgery during the six months prior to screening (or planned before final assessment).
- Women of child-bearing age if they are pregnant, planning a pregnancy during their time in the study or in the 12 weeks following giving birth. This is due to the effects of pregnancy on balance.
Key Trial Info
Start Date :
October 20 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 20 2019
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03278093
Start Date
October 20 2017
End Date
February 20 2019
Last Update
January 22 2019
Active Locations (1)
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1
National Hopsital of Neurology and Neurosurgery
London, United Kingdom, WC1N 3BG