Status:

COMPLETED

Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents

Lead Sponsor:

University of Arizona

Conditions:

Actinic Keratoses

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This proposed project will be an open-label, split face, randomized controlled pilot study. Up to 60 patients with diffuse facial actinic keratosis will be enrolled in the study. The purpose of this s...

Detailed Description

The purpose of this study to understand the change in skin appearance during and after the course of 5-FU cream in patients with AK, and compare how the appearance of skin inflammation changes with th...

Eligibility Criteria

Inclusion

  • Male and female, at least 18 years of age
  • Subject must have a diagnosis of actinic keratosis (at least 5 lesions on each side of the face)
  • Able to comprehend and read the English language

Exclusion

  • Subjects who do not fit the inclusion criteria
  • Concurrently have other inflammatory skin conditions.
  • Prior known allergy to any components to of 5FU cream, topical steroid ointment or vaseline.
  • • Subject who, in the opinion of the investigator, will be uncooperative or unable to comply with study procedures (i.e.: compliant with using 5-FU cream, topical corticosteroid or moisturizers
  • Those that are prisoners or cognitively impaired.

Key Trial Info

Start Date :

October 10 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2018

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03279328

Start Date

October 10 2017

End Date

July 31 2018

Last Update

June 25 2019

Active Locations (1)

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University of Arizona - Banner University Medicine Dermatology

Tucson, Arizona, United States, 85718

Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents | DecenTrialz