Status:

COMPLETED

Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions

Lead Sponsor:

University Hospital, Ghent

Conditions:

Breast Neoplasms

Radiotherapy

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The goal of this trial is to evaluate the effect of the prone crawl treatment position and/or accelerated schedule on acute and late toxicities, as well as quality of life and time management for brea...

Detailed Description

Locoregional radiotherapy after lumpectomy and axillary node dissection diminishes the locoregional recurrence risk at 10 years by 21,2 % in women with pathologically confirmed lymph node involvement....

Eligibility Criteria

Inclusion

  • Breast conserving surgery
  • AND Multidisciplinary decision of adjuvant whole breast + regional nodal irradiation
  • AND Informed consent obtained, signed and dated before specific protocol procedures

Exclusion

  • Mastectomy
  • OR Bilateral breast irradiation
  • OR Distant metastasis/metastases
  • OR previous irradiation to the thoracic, cervical or axillary region and overlap of fields with current treatment
  • OR life expectancy of less than 2 years
  • OR pre-existing conditions or comorbidities making toxicity evaluation difficult, e.g. skin disorders
  • OR pregnant or breast feeding
  • OR mental condition rendering the patient unable to understand the nature, scope and possible consequences of the study
  • OR patient unlikely to complete the study

Key Trial Info

Start Date :

September 15 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 9 2021

Estimated Enrollment :

61 Patients enrolled

Trial Details

Trial ID

NCT03280719

Start Date

September 15 2017

End Date

June 9 2021

Last Update

September 19 2024

Active Locations (1)

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Radiotherapy department, UZ Ghent

Ghent, Oost-Vlaanderen, Belgium, 9000