Status:

COMPLETED

Assessing Fluid Responsiveness With PWTT

Lead Sponsor:

Johannes Gutenberg University Mainz

Conditions:

Fluid Therapy

Monitoring, Intraoperative

Eligibility:

All Genders

18-80 years

Brief Summary

Pulse wave Transit time (PWTT) is a parameter calculated from ECG and pulseoximeter. It is supposed to help assessing the preload Status and guide intraoperative fluid therapy. This Project aims to va...

Detailed Description

PWTT is determined by measuring the beginning and the end of pulse wave duration and can be calculated as the time interval from the ECG R-wave peak to the rise point of the pulse oximeter wave. it c...

Eligibility Criteria

Inclusion

  • Adults 18 - 80 years old
  • elective open abdominal surgery
  • clinical indication for direct arterial blood pressure Monitoring
  • supine Position intraoperatively

Exclusion

  • under 18 years, over 80 years old
  • pregnant
  • no informed consent
  • systemic inflammatory response syndrome (SIRS) or Sepsis
  • Severe cardiac, coronary or vascular disease
  • Arrythmia
  • Cardiac valves anomaly
  • BMI \> 35
  • American Society of Anesthesiologists (ASA) physical status classification system: 4
  • Lung disease that excludes Ventilation with a tidal volume \>8ml/kg
  • esophageal pathology
  • planned prone position surgery

Key Trial Info

Start Date :

May 31 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 31 2019

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT03280953

Start Date

May 31 2016

End Date

January 31 2019

Last Update

July 30 2020

Active Locations (1)

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University Medical Center of Johannes Gutenberg University

Mainz, Rhineland-Palatinate, Germany, 55131