Status:

UNKNOWN

Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia

Lead Sponsor:

Assiut University

Conditions:

Gestational Trophoblastic Disease

Eligibility:

FEMALE

18-50 years

Phase:

PHASE2

PHASE3

Brief Summary

Gestational trophoblastic neoplasia (GTN) are malignant lesions that arise from abnormal proliferation of placental trophoblast. The pathologic conditions that make up this entity include invasive par...

Detailed Description

When reporting GTN data, it is useful to use both the FIGO anatomic staging system and prognostic scoring system . A FIGO score of 6 or less indicates low-risk GTN whereas a score of 7 or more identif...

Eligibility Criteria

Inclusion

  • Age: 18-50
  • BW: 50-100 kg
  • willing and consenting to be enrolled in the study
  • Absence of active vaginal bleeding which requires surgical intervention • - WHO score \<6

Exclusion

  • Renal and liver dysfunction or blood dyscariasis
  • high risk persistent gestational trophoblastic disease.

Key Trial Info

Start Date :

October 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2019

Estimated Enrollment :

170 Patients enrolled

Trial Details

Trial ID

NCT03280979

Start Date

October 1 2017

End Date

October 1 2019

Last Update

September 13 2017

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