Status:
UNKNOWN
The Effect of Menstrual Cycle On IL-6, TNF-α And Periodontal Status
Lead Sponsor:
Yuzuncu Yil University
Conditions:
Menstrual Cycle-Associated Gingivitis
Eligibility:
FEMALE
20-29 years
Brief Summary
Aim: Women's menstrual cycle is controlled by the secretion of sex hormones. Sex steroid hormones are thought to be affect to periodontal tissues, wound healing, periodontal disease progression and bo...
Detailed Description
Study Population Sixty women were initially included in this longitudinal, prospective study in Yuzuncu Yil University, Faculty of Dentistry, Department of Periodontology. The procedure was accepted...
Eligibility Criteria
Inclusion
- Inclusion criteria were:
- premenopausal women, age 20-35 to years;
- normal and steady menstrual cycle (25 to 31 days long);
- available for clinical examination;
- non-smoking;
- antibiotic therapy or use of nonsteroidal anti-inflammatory drugs within the past 6 months;
- healthy systemic status;
- normal body mass index;
- healthy periodontium.
Exclusion
- Exclusion criteria were as follows:
- pregnancy;
- use of oral contraceptives;
- metabolic or systemic condition that might affect the periodontium;
- antibiotic therapy or use of nonsteroidal anti-inflammatory drugs within the past 6 months;
- periodontitis;
- smoking and
- with the diagnosis of polycystic over or hyperandrogenism according to Rotterdam diagnostic criteria
Key Trial Info
Start Date :
July 26 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2018
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03281109
Start Date
July 26 2017
End Date
September 1 2018
Last Update
February 6 2018
Active Locations (1)
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1
Yuzuncu Yıl University
Van, Turkey (Türkiye), 65080