Status:
UNKNOWN
The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation
Lead Sponsor:
Canisius-Wilhelmina Hospital
Collaborating Sponsors:
Maastricht University Medical Center
Conditions:
Emphysema or COPD
Aneurysm
Eligibility:
All Genders
18+ years
Brief Summary
Background: Elastin is a unique protein providing elasticity, resilience and deformability to dynamic tissues, such as lungs and vasculature. Elastin fibers are characterized by their high affinity fo...
Eligibility Criteria
Inclusion
- Use of VKAs for at least 3 months
- Stop VKAs at short time
- Written informed consent
- Age ≥18 years
- Ability to comply with all study requirements
Exclusion
- Active malignancy or cured malignancy \<12 months prior to enrollment
- Use of maintenance dose oral corticosteroids
- Serious mental impairment
- Life expectation of less than 6 months on the basis of concurrent disease
Key Trial Info
Start Date :
October 31 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03285100
Start Date
October 31 2017
End Date
October 1 2018
Last Update
January 25 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Canisius Wilhelmina Hospital
Nijmegen, Netherlands, 6532SZ