Status:

COMPLETED

The Effect on Vascular Reactivity Using the Erythropoeitin Alpha on Incident Peritoneal Dialysis Patients

Lead Sponsor:

National Kidney and Transplant Institute, Philippines

Conditions:

Chronic Kidney Disease

Anemia

Eligibility:

All Genders

18-60 years

Phase:

PHASE4

Brief Summary

This is a prospective observational study on incident peritoneal dialysis patients on the effect of hemoglobin level and vascular reactivity using the generic erythropoietin alpha. The objective of th...

Detailed Description

This is an investigator-initiated study partially subsidized by the Unilab- Biomedis- Biomedis by providing the drug Renogen® 4,000 units/vial, H2 Receptor Blocker and Ferrous Sulfate. The supporting ...

Eligibility Criteria

Inclusion

  • Patients aged 18 to 60 years old
  • Newly diagnosed ESRD patients started on peritoneal dialysis for less than 3 months not previously on any type of EPO. If previously on a different brand of EPO, patient will have a washout period of 4 weeks.
  • Can follow up at NKTI OPD for at least 3 months
  • Can take oral iron supplements

Exclusion

  • Known allergy to EPO
  • With severe illness such as congestive heart failure Class III - IV, acute myocardial infarction, infection within 1 month of starting the study or had a severe hepatic disease.

Key Trial Info

Start Date :

October 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2017

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03286712

Start Date

October 1 2015

End Date

May 1 2017

Last Update

September 18 2017

Active Locations (1)

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Department of Adult Nephrology; National Kidney and Transplant Institute

Quezon City, National Capital Region, Philippines, 1101