Status:

COMPLETED

Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility

Lead Sponsor:

Mayo Clinic

Conditions:

Enhancement of the ADR During Colonoscopy

Eligibility:

All Genders

50+ years

Phase:

NA

Brief Summary

The investigators hypothesize that spraying peppermint oil containing L-menthol onto the colonic mucosa during colonoscopy will relax smooth muscle allowing better colonic visualization.

Eligibility Criteria

Inclusion

  • Screening colonoscopy
  • Age 50 years and older
  • Able to give consent

Exclusion

  • No consent obtained or adult lacking capacity to consent
  • Do not reach cecum on colonoscopy
  • Renal impairment (defined as CrCl \<30 ml/min)
  • Allergy to study peppermint oil solution
  • History of colon resection
  • Inflammatory bowel disease
  • Known colorectal neoplasia
  • Non-correctable coagulopathy
  • Pregnancy or lactating
  • Prisoners

Key Trial Info

Start Date :

November 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 10 2019

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT03286764

Start Date

November 1 2016

End Date

September 10 2019

Last Update

April 3 2020

Active Locations (1)

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Mayo Clinic in Arizona

Scottsdale, Arizona, United States, 85259

Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility | DecenTrialz