Status:

WITHDRAWN

Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use

Lead Sponsor:

Emory University

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

Chestnut Health Systems

Conditions:

Opioid-Related Disorders

Behavior, Addictive

Eligibility:

All Genders

18-25 years

Phase:

NA

Brief Summary

The study assesses whether adding a behavioral intervention, known as the Adolescent Community Reinforcement Approach (A-CRA), to the treatment of individuals already receiving buprenorphine/naloxone ...

Detailed Description

Buprenorphine is one of the medication assisted treatments approved by the FDA for opioid use disorders. Treatment with buprenorphine/naloxone may reduce the risk of opioid overdose and lower the occu...

Eligibility Criteria

Inclusion

  • have met DSM-5 criteria for severe opioid use disorder
  • no sensitivity to buprenorphine or naloxone
  • no further medical/addictive conditions that require immediate medical attention
  • ability to read and provide informed consent
  • intent to remain in the area for the duration of the study
  • able to receive outpatient care
  • agreed to use an acceptable birth control method throughout the duration of this study (female participants)

Exclusion

  • endorsement of imminent and serious suicidality
  • medical conditions that take precedence over the presence of treatment for an addictive disorder
  • history of an adverse reaction to buprenorphine/naloxone
  • current substance use or psychiatric condition requiring a level of care higher than outpatient
  • pregnant, nursing or planning pregnancy during the extent of the treatment trial(female participants)

Key Trial Info

Start Date :

January 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 9 2020

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03287180

Start Date

January 1 2019

End Date

June 9 2020

Last Update

July 28 2020

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