Status:

UNKNOWN

MRI Measurement of the Effects of Deep Neuromuscular Blockade on the Abdominal Working Space During Laparoscopy

Lead Sponsor:

Radboud University Medical Center

Collaborating Sponsors:

Merck Sharp & Dohme LLC

Conditions:

Neuromuscular Block

Surgery

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

During laparoscopy, a surgical working space is obtained by creation of a pneumoperitoneum. Optimal surgical conditions are essential to ensure the patient's safety. A meta-analysis on studies compari...

Detailed Description

Objective: To establish the influence of deep neuromuscular blockade (NMB) on the abdominal working space during laparoscopy. Study design: A single center prospective cohort study Study population:...

Eligibility Criteria

Inclusion

  • scheduled for laparoscopic donor nephrectomy
  • obtained informed consent

Exclusion

  • Unable to provide informed consent
  • known or suspect allergy to mivacurium, rocuronium or sugammadex
  • neuromuscular disease
  • indication for rapid sequence induction
  • Being unable to undergo MRI due to any reason (e.g. non MRI-compatible implants, epilepsy)
  • BMI\>30 kg/m2
  • American Society of Anesthesiologists (ASA) classification \>2

Key Trial Info

Start Date :

May 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2019

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT03287388

Start Date

May 1 2019

End Date

December 1 2019

Last Update

April 2 2019

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