Status:
COMPLETED
Dysregulated CNS Inflammation After Acute Brain Injury
Lead Sponsor:
University of Kentucky
Conditions:
Traumatic Brain Injury
Aneurysmal Subarachnoid Hemorrhage
Eligibility:
All Genders
18-101 years
Brief Summary
By doing this study, the investigator hopes to learn how the levels of important proteins involved in inflammation change over time in patients with acute brain injury. The total amount of time partic...
Detailed Description
This pilot project is a prospective, observational study in 20 patients who are admitted to University of Kentucky (UK) Chandler Medical Center with a diagnosis of severe, non-penetrating traumatic br...
Eligibility Criteria
Inclusion
- severe, non-penetrating TBI or aSAH
- must have a ventriculostomy (EVD) placed by the UK Neurosurgery service within 12 hours of primary traumatic episode
Exclusion
- non-survivable brain injury or other organ system injury
- life expectancy is five days or less
- penetrating TBI
- status epilepticus upon arrival to the hospital
- severe ischemic heart disease or congestive heart failure, myocardial infarction, or spinal cord injury
- Takotsubo cardiomyopathy secondary to the SAH
- active cancer or have been treated for cancer within the previous 6 months
Key Trial Info
Start Date :
January 2 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 24 2019
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03287557
Start Date
January 2 2018
End Date
May 24 2019
Last Update
August 29 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Kentucky Deparment of Neurosurgery, UK Chandler Hospital
Lexington, Kentucky, United States, 40536-0298