Status:
COMPLETED
Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI
Lead Sponsor:
University Hospital, Bordeaux
Collaborating Sponsors:
General Electric
Conditions:
Spondyloarthropathy
Tendinopathy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to accurately map calcaneal fibrocartilage using TE = 0 ms imaging, and then apply measurements of our control population to SpA patients with peripheral enthesis study us...
Detailed Description
The human body contains a lot of tissue components with short T2 (transversal relaxation time) that are not or only poorly detected on conventional T2-weighted MR sequences. These components are mostl...
Eligibility Criteria
Inclusion
- Age ≥18 years,
- Covered under social security
- Informed signed consent
- Additional criteria for each group:
- GROUP 1: HEALTHY VOLUNTEERS
- Absence of diagnosis of spondyloarthropathies
- No previous history of plantar support and pain, calcaneal tendinopathy, infiltration or surgery
- GROUP 2: SPA + NON-SYMPTOMATICS AT THE CALCANEEN FIBROCARTILAGE LEVEL
- ASAS criteria axial or appendicular
- No previous history of plantar support and pain, infiltration or surgery
- Prescription Achile's tendon MRI with injection of contrast agent (macrocyclic gadolinium) in usual care.
- GROUP 3: SPA + SYMPTOMATICS AT THE CALCANEEN FIBROCARTILAGE LEVEL
- ASAS criteria axial or appendicular
- Clinical suspicion of rheumatic enthesopathy
- Absence of a history of calcaneal infiltration or surgery
- Prescription Achile's tendon MRI with injection of contrast agent (macrocyclic gadolinium) in usual care.
- GROUP 4: MECHANIC TENDINOPATHY
- Clinical diagnosis of calcaneal mechanical tendinopathy
- Absence of diagnosis of spondyloarthropathies
- No any previous history of plantar support disorder, calcaneal infiltration or surgery
- Prescription Achile's tendon MRI with injection of contrast agent (macrocyclic gadolinium) in usual care.
Exclusion
- Age less than 18 yrs old
- Pregnant or lactating woman
- History or presence coronary pathology
- Septic arthritis
- Immunodeficiency.
- Contra-indication for MRI exam
- Legal protection
- Additional criteria for GROUPS 2, 3 and 4:
- History or presence of renal insufficiency
- Allergy to macrocyclic gadolinium
Key Trial Info
Start Date :
April 7 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 21 2023
Estimated Enrollment :
121 Patients enrolled
Trial Details
Trial ID
NCT03287596
Start Date
April 7 2018
End Date
January 21 2023
Last Update
February 22 2023
Active Locations (1)
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1
CHU de Bordeaux
Bordeaux, France, 33076