Status:

UNKNOWN

Therapeutic Effect Of Luteolin Natural Extract Versus Its Nanoparticles On Tongue Squamous Cell Carcinoma Cell Line

Lead Sponsor:

Cairo University

Conditions:

Tongue Neoplasms

Carcinoma

Eligibility:

All Genders

Phase:

EARLY_PHASE1

Brief Summary

In vitro study to examine whether luteolin and nano-luteolin exert an inhibitory effect on tongue squamous cell carcinoma cell line by inducing apoptosis, and to assess if nano-luteolin has more effic...

Detailed Description

This study is conducted to examine whether luteolin and nano-luteolin exert an inhibitory effect on tongue squamous cell carcinoma cell line by inducing apoptosis, and to assess if nano-luteolin has m...

Eligibility Criteria

Inclusion

  • Squamous cell carcinoma cell lines (OSCC, TSCC and HNSCC).
  • Luteolin 5,7,3',4'-tetrahydroxy-flavone (MeSH term).
  • Application of luteolin as a chemotherapeutic drug.

Exclusion

  • Any cancer cell line other than OSCC, TSCC and HNSCC cell lines.
  • Luteolin glycosides.

Key Trial Info

Start Date :

November 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2019

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT03288298

Start Date

November 1 2017

End Date

April 1 2019

Last Update

September 20 2017

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Therapeutic Effect Of Luteolin Natural Extract Versus Its Nanoparticles On Tongue Squamous Cell Carcinoma Cell Line | DecenTrialz