Status:
COMPLETED
The Effects of Dark Chocolate Implementation in Elite Athletes
Lead Sponsor:
University of Roma La Sapienza
Conditions:
Oxidative Stress
Athletes Heart
Eligibility:
MALE
18-35 years
Phase:
NA
Brief Summary
Dark chocolate (DC) is rich in epicatechin which augments nitric oxide (NO) production through endothelium-dependent influences. The increased bioavailability and activity of NO have been demonstrated...
Eligibility Criteria
Inclusion
- Elite male athletes volunteers, aged between 18 and 35 years
Exclusion
- they suffer from an allergy to cocoa or any of the ingredients contained within either of the chocolate bars
- they have a low platelet count (\< 170 x 10E09/ L)
- they are taking aspirin or aspirin-containing drugs, other anti-inflammatory drugs, or any drugs or herbal medicines known to alter platelet function or the haemostatic system in general (without a minimum washout period of one month)
- they are taking fish oils or evening primrose oil, or fat soluble vitamin supplements within the last 4 weeks
- they have unsuitable veins for blood sampling and/ or cannulation
- they have a BMI below 18 or above 35 kg/ sqm
- they are taking any medicine known to affect lipid and/or glucose metabolism
- they are suffering from alcohol or any other substance abuse or are having eating disorders
- they have any known clinical signs of diabetes, hypertension, renal, hepatic, hematological disease, gastrointestinal disorders, endocrine disorders, coronary heart disease, infection or cance
Key Trial Info
Start Date :
September 25 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2018
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03288623
Start Date
September 25 2017
End Date
November 1 2018
Last Update
April 17 2019
Active Locations (1)
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1
Sapienza University of Rome, Policlinico Umberto I
Rome, Italy, 00161